The HyperCube Institute

A research institute on strong and orphan diseases

The HyperCube Institute focuses on rare and orphan diseases often neglected by research

The HyperCube Institute  is an independent French endowment fund (fonds de dotation) which supports French and foreign research entities to benefit freely from a technical assistance by the Institute's team of scientists as well as from the Institute's in-house solutions.

The purpose of the fund is to participate in public interest research projects in the field of rare diseases, orphan diseases and public health matters in partnership with top-tier institutions and share the results with the wider community.

Our main sponsor is  Bearingpoint_logo

Our work

Our expertise

Data-Mining & Health Science

Life Science

Interests in Life Science research.

The HyperCube Institute develops data analysis technologies that can be implemented in research projects; we simplify the use of tools to analyse large datasets. Those tools allow for the extraction from complex databases of the desired combination of factors for the phenomena under study

Close-up Of Doctor Using Laptop In Front Of Stethoscope At Desk

Health data digitalization

A major opportunity and significant stakes

In order to optimize medical decisions throughout a patient's lifespan, the consolidation of medical data is a required step. The analysis of those "big data" then constitutes a major stake

Green laboratory

Rare and orphan diseases

Left behind by traditional research

A disease is considered as rare when it affects less than one patient out of 2000. Rare diseases are very often left behind by traditional research as they do not offer enough economic potential to develop a therapy given the small number of affected patients. Research investments are therefore often insufficient

Research in action

The scopes of Application

The scopes of Application include research on rare diseases

Characterization of risk factors in particular when combined for a given disease, including genetic epidemiology: works and publications in collaboration with the Pasteur Institute

Characterization and classification

Understanding the combinations of factors associated with or leading to a given phenotype (for example aggressiveness)

Response to a treatment

Characterization of good and bad respondents to given treatments, under post-hoc clinical tests analysis

Detection and diagnosis

Detection and diagnosis of diseases from bio samples

Prognosis: explication and forecast

Which combinations of characteristics can be found among patients with unfavorable prognosis vs. favorable prognosis?


Characterization of patient profiles associated with a given form of toxicity of a treatment

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